The latest WordPress version 5.5.2 works fine with Oxygen Builder. No issues found so far.
It is always smart to do create a backup of your site before you do the update though. Just in case.
My sites just auto updated to WP 5.5.3 this morning behind my back! But so far no problems on two site I have been working on.
Yeah, I hate the auto update feature. I always turn it off with a string in wp config. But some servers override that apparently.
It works fine on 5.5.3 for me as well.